S.T.A.L.K.E.R., part one

Originally, as a stalker, we had to both survive in and live off the environment, and could suffer the effects of hunger, exhaustion, radiation and health...

Yavorsky:
After a series of play-tests we decided to simplify the micromanagement of the player's survival parameters and make it all less complicated compared to the original implementation. Thus, we removed the need to sleep and eat. Food, however, remains in the game and serves specifically to restore your health a bit (a kind of alternative to medkits). Exhaustion comes if you are carrying too much weight - getting overloaded with weapons, items, artifacts, food etc (each object in the game has weight) does not let you run or even walk (depending on the weight you're trying to carry).

Keeping an eye on your health bar and staying away from radiation and anomalies remains very important. Radiation sickness (you will see a characteristic visual effect and radiation sign on screen) makes you lose health very quickly, so make sure you've got anti-rad pills or vodka with you to cure the wounds.

Speaking about wounds, depending on the injury type, you may start bleeding (apply bandages to stop it), so watch out as other NPCs/creatures may hunt you down by traces of blood on the ground (you may do the same to them).