The Spider-Man comic book writer who created Madame Web's villain is just as confused by the trailer as you are. J. Michael Straczynski, who created the antagonistic Ezekiel Sims, shared his thoughts on the Sony/Marvel trailer after the clip attracted chatter online.
"And well, this just happened," he tweeted, attaching a link to an article headlined 'Madame Web’s First Trailer Introduces Spider-Women, Deep-Cut Villain'. "It's definitely the character I created for Spidey, but it feels like they may have merged it with Morlun a bit. (Don't ask for any details because this is the first I'm hearing of it, so my guess is as good as yours.)"
In Madame Web, Ezekiel is played by Tahar Rahim. In the comics, he's a rich businessman who ritualistically gained powers similar to Spider-Man's. Judging by the movie's trailer, it seems that his on-screen counterpart can also see the future.
The movie stars Dakota Johnson as the clairvoyant titular character, who, by day, is Cassie Webb, a paramedic. She's joined by Sydney Sweeney, Celeste O'Connor, and Isabel Merced as Julia Carpenter, Mattie Franklin, and Anya Corazon.
