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Rooney Mara and Channing Tatum star in trailer for Steven Soderberghs Side Effects: watch now

The first trailer has emerged for Side Effects (formerly The Bitter Pill ), Steven Soderbergh’s supposed final film before retirement, starring a washed-out Rooney Mara and a ruggedly supportive Channing Tatum.

The two stars play a successful New York couple who find their lives beginning to unravel when a new drug prescribed by Mara’s psychiatrist (Jude Law) produces some unexpected and destructive side effects.

If you’re thinking dizziness or nausea, think again. It’s a little more serious than that… particularly when somebody ends up dead.

Take a look at the new trailer, below…

Part psychological pot-boiler, part indictment of the pharmaceutical industry, it looks as though Soderbergh has conjured up a taut little thriller, with a cast capable of lifting it beyond an admittedly melodramatic premise.

Co-starring Catherine Zeta-Jones, Side Effects will open in the UK on 15 March 2013. Always read the label.

George was once GamesRadar's resident movie news person, based out of London. He understands that all men must die, but he'd rather not think about it. But now he's working at Stylist Magazine.