Note: You'll need to complete "Family Matters" to enter Novigrad from any bridgeway.
Prerequisite: None | Suggested Level: 13
It's a little unclear whether you get this quest as you enter Oxenfurt or when you check out the Notice Board. Either way, you'll get a marker on a nearby island. Head there to meet a Rock Troll who's apparently been brought into the Redanian army. After a rather interesting conversation, you'll learn that he needs some red paint.
Head back into Oxenfurt and check with the Merchant in the marketplace. Buy paint from him and return to the Rock Troll. You can then choose to help him paint or not; either choice will wrap up the quest.
Gwent: Playing Innkeeps
Prerequisite: None | Suggested Level: N/A
There's Gwent to be played in Novigrad, and you can read about it on the Oxenfurt Notice Board. Start by visiting Stjepan, now marked on your map. Beat him in a round, and he'll tell you of two more innkeeps looking to play. Best both of them to finish the quest.
Contract: The Oxenfurt Drunk
Prerequisite: None | Suggested Level: 26
You can get this contract from the Oxenfurt Notice Board. Once you do, speak to the Redanian captain near Radovid's boat to learn of a beast that's been killing around the city. Talk to the captain for more information on the bodies and witnesses.
Step two is to head to the city inn and speak to the booze-heavy woman there. She'll tell you about the attack she survived. After this talk, you can check the alleyway next to the tavern with your Witcher Senses to find a discarded bracelet belonging to the attacker.
Now you need to visit the medic on the southern shore of the city. After a talk, he'll let you in to examine the bodies. Do so to figure out the killer's identity: a katakan. Return to the inn and buy a drink to get some alcohol in your system. This will summon the beast.
Stagger into the street, and Geralt will mumble like a drunkard. You'll have to do this in three different spots to get the creature's attention. After a few blows, it will flee. Use your Witcher Senses to track it to a hut to the north. Climb the ladder outside to drop in on the beast, then finish it off. Return to the Redanian for a reward.
Contract: The Creature from Oxenfurt Forest
Prerequisite: None | Suggested Level: 35
This contract comes from the Oxenfurt Notice Board. Ride to the small camp east of the city and speak to Hans; he'll tell you of some beast that's been prowling the area. Head to your new marker and use Witcher Senses to examine a corpse and a blood smear. The search area will widen, so keep your senses up to find a severed arm and a trail of blood droplets.
Follow these, and you'll soon reach the end of the trail. You'll open a new search area, but your target is easy to find. Head for the swarm of birds you see above - this will send you right into an archgriffin's nest.
Return at nighttime to battle the beast. This is a high-level fight, so have some oils (and maybe a decoction) at the ready; Aard is also effective. Once you’re victorious, return to Hans for a reward. If you found the contract in the griffin's nest earlier, you'll get more.