2. Hand Cannon (Dead Space 2)
The serious game: Dead Space is all about immersive horror. Isaac Clarke stumbles onto a massive conspiracy involving monsters, Unitologists (not to be confused with Scientologists), and a weird alien marker. In the sequel, he's thrown even deeper down the rabbit hole, and finds himself face-to-face with giant, absurd creatures as he slowly loses his grip on his humanity.
The silly weapon: A foam finger. Get it? The "Hand Cannon" is unlocked after beating the game on the hardest difficulty, and is likely the strongest weapon in the game. It doesn't need ammunition, can be fired as fast as you can pull the trigger, and absolutely obliterates anything it hits. Oh, and when Isaac fires, he actually says "Pew, pew, pew!" or "Bang, bang!" This is definitely a huge departure from the other weapons, and doesn't fit within the dark, frightening tone of Dead Space one bit. But it sort of works if you imagine that beating the game on Hardcore leads to Isaac finally going full-bore crazy.