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  1. Games
  2. Action RPGs
  3. The Outer Worlds 2

How to cure Zyranium poisoning in Outer Worlds 2

Guides
By Jasmine Mannan published 1 November 2025

If you’ve been unfortunate enough to face Zyranium poisoning then here’s how to get rid of it

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Outer Worlds 2 Zyranium poisoning
(Image credit: Obsidian)
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Get Outer Worlds 2 Zyranium poisoning and you’ll find you have reduced health and cough very loudly (which can really ruin your chances at remaining stealthy). And, oh yeah, if you don’t fix this issue soon enough then it can lead to death.

Having the right Outer Worlds 2 companions can keep you healed up while suffering from Zyranium poisoning but ideally you want to get rid of the problem. Fortunately, there are multiple ways to cure it. You may need to fork out some cash in order to do this though, so be sure you’ve got the money to pay your bill. We’ve covered the different methods below.

To prevent getting Zyranium poisoning again in the future, you can also use our tips below to stay safe and hopefully save yourself a pretty penny so you don’t have to pay more Doctor’s fees again. It's a problem you'll encounter frequently as you explore The Outer Worlds 2, so it's best to be prepared.

How to cure Zyranium poisoning

The Outer Worlds 2 Central Dispatch shootout with protectorate forces

If you’re have Zyranium poisoning in The Outer Worlds 2, then there are two ways to clear this status effect. The first is to find an AutoDoc. This is one of the easiest ways to cure Zyranium poisoning and can be found throughout every location in the Outer Worlds 2.

Using an AutoDoc station will totally refresh your HP, remove any status effects (including poisoning), and give you two full inhaler chargers for free. It’s worth noting that each AutoDoc station can only be used once to restore Inhaler Charges.

The other option is to find a doctor. You can find a multitude of NPC Doctors in different cities throughout the universe, such as Arcadia. They can heal damage and poisoning for a charge. If you’re struggling to find Doctors then asking locals where you can find one may point you in the right direction.

How to prevent Zyranium poisoning

If you want to be more proactive in avoiding Zyranium poisoning, then there are a couple of things you can try. The first is to get some Gas-Energy Deflection Apparatus. You can find this by completing the Above and Beyond Repair sidequest. This Outer Worlds 2 gadget can help prevent Zyranium poisoning as shields you from Gas and bullets for a short time.

You should also be careful about using your inhalers as this will slowly build up your toxicity. This can lead to a drug crash or even Zyranium poisoning. Some Outer Worlds 2 flaws, like Teetotaler, can increase the inhaler toxicity even further so be sure to be mindful when over using them.

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Jasmine Mannan
Jasmine Mannan
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A former Hardware Editor at GamesRadar+, now freelance writer, Jasmine is an avid lover of all the games everyone else dares to call terrible. She's sunk thousands of hours (and dollars) into League of Legends and Overwatch 2 and enjoys multiplayer games that allow her to relax after her days of writing at a range of sites, including EsportsInsider and PCGN.

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