There are two horrible truths about hospices: They're depressing places to hang out in, and they're steady, reliable business. Death is the only constant in life, and while it may seem awful to work in a place where terminally ill patients go to die, we don't doubt that it's gratifying work for those who can ease the suffering of the doomed. Still, these places have to make money to outlast their clients, which is where you come in.
How it could work as a game: Here's the bizarre thing about running a hospice: The more people that die there, the more money you make. You'd start off small, with a one or two-bedroom unit. But as you accrue more patients and income, you'd be able to expand your workspace, buy more comfortable beds, and pay your staff enough to not want to jump off a bridge after having seen so many people pass away. It's all terribly morbid, to be certain, but hey--there are bills to be paid.