Waller is the no nonsense woman that offers Slade a position in Suicide Squad, a role that she filled in the comic books as well. Ms. Waller is a high ranking government official that finds super villains to go on risky missions, usually ones too morally grey (or outright evil) for heroes like Batman to approach. It’s a dirty job, and one that puts her face to face with murderers, but she always stays in control of the situation. It helps that she outfits each baddie on her squad with an explosive collar that will kill them should they get out of line.
In Origins, despite her brief appearance, she’s voiced by celebrated actress Cch Pounder. If you don’t recognize her from The Shield or Avatar, longtime DC fans will likely remember her playing Waller in the Justice League animated series. She owns the role on that show, something we hope continues in this heavily implied Suicide Squad game. She won’t see much action, so we could see her taking a role similar to Alfred’s in Origins: the voice in your ear pushing you to your next goal. But don’t expect her to be as nice about it as Alfred.