Resident Evil 5 Strategy guide and Boss guide

Welcome to the GamesRadar Resident Evil 5 Strategy guide and Boss guide

First things first: fairly obviously this guide contains MAJOR GAME SPOILERS. The last page (page 4) contains images from the end of the game - so if you don't want to know what happens steer clear of it.

This guide is not a walkthrough (something we decided wasn't overly useful in Resident Evil games) instead it is a strategy for playing the game, that points out useful hints and tips for progressing through each of the Acts. It also contains sections on where to find the best weapons and detailed boss battle strategies.

Look out for our BSAA emblems guide coming later today. 

The guide was screen captured from the 360 version but will work for the PS3 version as well.

As always any suggestions for improvement will be considered to make this guide as definitive as possible.

Acts 1 and 2 | Acts 3 and 4 | Act 5 | Act 6 

Chris and Sheva arrive at Kijuju town in search of Irving; a nasty piece of work who’s up to no good. It’s clear they’re unwelcome, but they never imagined it would turn out to be this hostile.


Want to beat the executioner? Here’s how to do it… You’ll need ammo, so knife the piles of fruit for hand grenades and bullets.

There’s a stash of grenades on the highest roof (see ‘Hide and Seek’, below) which come in extremely handy, and more inside the two houses in the town’s middle. Hurl these one at a time, and when the executioner drops to his knee run in close and punch him to cause some extra damage.

Don’t forget to use environmental factors. There are red barrels dotted all over town that will eat at chunks of the executioner’s health, and power transformers positioned high up that will stun him – make sure you take advantage of them. Then let rip with the uzi when he’s down to finally defeat him.


Think you can save the blonde girl early on in Act 1-2? Think again. Grab the shotgun from the nearby hut and prepare for a battle: as soon as she’s hit, a giant snake-like growth bursts from her head!

The golden rule here is to keep back. Stay back even when she’s on the ground and you should be okay, especially if you empty the shotgun into her growth.


Finding the town fight too tough? Hide instead:

- Start off by barricading yourself in the opening house by pushing the two bookcases against the entrances
- When the Executioner majini appears, run past, take a left, hop the fence and climb the ladder to your left
- You’ll now be above the room you began in. Climb the ladder in the back to reach the roof of the building
- Up here you’ll find a stash of hand grenades to keep the majini at bay. Not that you’ll need them…
- Enemies can only climb up the roof by the ladder or the ladder itself. Apart from the Executioner, who can’t reach you at all!

This act’s most powerful weapons:


Sprint past the Executioner majini once he destroys the gate. The VZ61 is on the right, past the final building

Ithaca M37

Boost Sheva up the first two broken ladders to spot and collect the Ithaca M37 shotgun hut key. It unlocks the blue door of the small hut opposite the balcony the blonde girl is attacked on. You can’t miss it

The first boss is an easy one, provided you follow these instructions:

Collect the furnace key from the dead body by the control panel and head back the way you came

Uh oh! Don’t bother tackling it head on. Once Uroboros appears it’s time to retreat back to the furnace

There are two upright gas canisters. Run in a clockwise route and knock each of them over

Then lure the Uroboros into the furnace after it’s swallowed a gas can. Aim for the can and… boom! With the Uroboros licking its wounds there’s just enough time to kill it off

Hit the switch by the furnace’s right door to close both exits and burn the oily monster to death

1. Your first BSAA token can be spied from the small balcony of the large house, after you’ve grabbed the shotgun key. Shoot these tokens for lots of unlockables.

2. Once you’ve climbed the gooey stairs and the subsequent ladder you’ll find a door. Before breaking it, turn left, jump the gap and raid the box for plenty of gold.

3. When you hop in the mine kart you’ll need to aim to the right and quickly shoot two trip wires. And that’s it… Not as long as Resi 4’s mine kart ride, is it?

The BSAA pair manage to escape Kijuju and its oily monster, only to find the mines and surrounding desert populated by infected townsmen and far nastier creatures than ever imagined.


When you leap the gap in the bridge a Resident Evil 4 set-piece returns for a second bite… Ready your weapon as the truck hurtles forward and aim left. When the truck pulls level with the nearby barrels shoot the left one to destroy it. A dozen majini will follow it, so use the other barrels to take several out at a time and you should survive this section easily enough.


You’ll eventually explore a building and boost Sheva over to a nearby rooftop. It’s time to go solo, but you need to make sure that Chris has the rifle before splitting up though. You then drop down the hole to your right once Sheva’s landed. You’ll need to cover Sheva for this segment of the game – don’t shoot the barrel when she’s near or it’s game over. She can deal with the majini on her level, so pick off those on the stairs and in the street below instead.


Your first chainsaw majini’s a nightmare, and he needs to be defeated to continue:

- Employ the same tactics as the executioner: use transformers and grenades, and run in close when he drops to one knee
- Make sure you use every explosive barrel that you possibly can to speed things up – they’re great for killing the villagers who jump over the walls.


When Irving exits via the window you need to grab the rifle (in the locker) and take cover below the window – this is important, or you could die. Squeeze LT when the turret’s reloading to pop out and shoot the gunner.

The act's most powerful weapons:


The H&K MP5 is impossible to miss. It’s in the shiny crate in the opening room, over to your left


After Kirk’s given you helicopter support push into the building the majini burst from. The S75 rifle’s there

Dragunov SVD

The Dragunov SVD rifle’s available immediately after Irving appears and escapes. Raid the lockers to your left.

The second boss is best tackled from both sides - co-op players have it easy!

Duck into the huts and pick up the proximity mines inside. Be wary of the Popokarimu’s swooping attacks: a button prompt will flash up on the screen if it swipes

Lay the proximity mines on the main path in between yourself and the Popokarimu. If it runs past it don’t panic; just run past it (he’s pretty slow) and lure it to you once more

When the mine works, Chris and Sheva need to fire into its fleshy underbelly. Repeat the mine trick when the Popokarimu rights itself and it’ll be dead in minutes.


Act 2 finishes off with a lengthy on-rails chase. Trucks will soon appear from both sides, so prioritise these over the biker majini. The early biker waves are also separated by three short quick-time event segments, and when you reach the roadblock just ignore the barrels.

Boss three appears straight after the chase. Get ready for more QTE dodging:

All of the Ndesu’s attacks can be countered. The stamp is stopped by shooting its foot, and its charge is ended by hitting the Ndesu’s face

Inflict enough damage and parasites will burst from the skin. Pop them both to coax a larger parasite out of the Ndesu’s back… and then blow it away!

Now it’s mad. When the troll rips up the road switch your fire to the rock. Get enough shots in and it will crumble before you take any damage

Another four parasites will burst from the Ndesu, followed by the giant parasite. Keep plugging these to kill the troll for good

If he picks up a pylon get ready to hit X (360) or square (PS3). Whenever the Ndesu takes a swing press X (360) or square (PS3) to duck under its attack. Then return the favour with some hot lead

Most of the enemies in the dark mine grow a giant head tentacle. Whoever has the lamp can’t put it down in the water, so keep them at the rear.

Next page: Acts 3 and 4


  • TotalKillLOL - June 22, 2009 1:44 a.m.

    Still an awsome game and great graphics and display. although I hate how long the last level takes
  • DantezGirl - June 11, 2009 10:37 a.m.

    Very Cool Game Thaanks For The Help
  • Garry - April 13, 2009 8:33 a.m.

    I have dis game It sucks my head. The town wars i think second wars in starting of game it is sooooooooooo difficult. There r infinite Zombies.
  • Redfield32 - April 12, 2009 9:14 p.m.

    Another RE game after this would kinda be umm weird. I mean you killed the Wesker clone umbrella is f*cked over now what? Be like Final Fantasy and do what happened before RE and play as Umbrella Corp instead of BSAA? Im not saying it would be bad I'm just saying what else is there to add really? Im only at the part with the native guys.
  • GYJX - March 29, 2009 7:04 a.m.

    Ok guys Im new so what up To the point Im not good at english but I going to try.... I know a really easy way to kill Wesker at the volcano, it took me less than 5 minutes on veterans mode which is the third level cause once you beat the game on that level it comes a harder level. Anyway, here I go When you hit the rock so Sheva can jump to get to high groud Wesker follows you, he rise his arm, we all know that, we also know that we have to hit his back so he can show the orange thing on his chest. I hope that you guy can understand me..... When he shows that orange thing on his chest his going to walk towards you, shoot the orange thing till he looks hurt I mean he is not going to move get close to him and the circle button will show up on the screen this is on PS3 Chris will jump to weskers back and he is going to ask Sheva to shoot the orange thing Sheva is going to say that she cant shoot that thing unless she shoots through Chris too so instead of that I dont know what options you have as Sheva but she uses her knif and start to slash wesker if you do that correctly Chris is going to jump to the ground and slash his back too and there his dead Sorry for my english I hope that you guy understand me please if you have any questions or you kill wesker the way I did please I beg Send me a mail to this
  • tylerlldsarg56 - March 27, 2009 12:51 a.m.

    its ok in scarinest i guess ive bout beat it
  • MrDanHalen - March 26, 2009 6:26 p.m.

    OK 2 things to add. 1) you can do more damage to Jill by having Chris/Sheva hold her while the other shoots the device on her chest... takes 4 tries instead of 8 2) Wesker is a clone (the whole wesker family are just clones).... just because he looks dead, does not mean he's gone forever.
  • Nefarious1 - March 24, 2009 1:10 a.m.

    @phoenix_wing: your name alone suggests "the return". I seriously hope that the RE series continues on into the distant future. Just want them to bring actual ZOMBIES back to the series... Maybe a 2 player CO-OP S.T.A.R.S mansion/underground facility revisited.
  • Nefarious1 - March 24, 2009 12:53 a.m.

    young gamers...remember, a very high percentage of RE is preparation, timing and alot of hand cannon recoil. 1st thing I would suggest to all who are having problems with Bosses and such is to MAX out your Magnums. Very few baddies can stand a blast from one of them let alone two (head) shots. Hit those missions hard, sit back, relax and push the limits of the'd be suprised at what u can get away with when u get in close enough to most baddies. Beating the game in -5 hours is very reasonable once you've learned your enemies "comfort zones".
  • Samael - March 22, 2009 5:59 p.m.

    "(ignore Chainsaw No 2)" Ugh, easier said than done. And what about the third chainsaw guy that comes when you're covering Josh? God I hate them!
  • phoenix_wings - March 17, 2009 7:19 a.m.

    I surprisingly didn't have too much difficulty with the bosses. Unfortunately, I didn't know that you could just run around and not blow through all of your ammo on Wesker...I should have read the guide first. Lesson learned. RIP Wesker...I've got to say that the best way to go would have to be in a volcano...I really hope he didn't make a clone of himself or something. Don't get me wrong, I love the RE series, it's just that I think it's time to close the book on this iconic series. And of course the reCaptcha is Continued Dalai
  • HorrorGod - March 17, 2009 6:16 a.m.

    I just beat RE5 today. As a fan of the series (Resident Evil 1 was the reason I bought a Playstation in '96) I have to say I think this was the best one yet. It was nice that it came back to the original characters that started it all. (After Leon got his own game with 4) Anyway, I just wanted to add to the tips and let everyone know you can defeat Wesker in the end with just a QTE. After you beat up the rock and have Sheva join you, you will have the last battle with Wesker in the middle of the circle area. DON'T RUN AWAY. I was screwed on ammo on this point and I could NOT beat him. I would shoot and shoot until his weak spot would show, and I'd shoot more, until my guns went "click". Finally I just ran up to him to see if I could do a QTE (when his weak spot was visible on his chest) and it allowed me to have a QTE. I held him down and Sheva began slashing away with her knife. BOOM, he was down and out. MUCH easier than what other people have been saying on forums (about stocking up on ammo and blasting it.) Hope this helps anyone who may be stuck at this part.
  • darknessexzero - March 17, 2009 3:21 a.m.

    I think wesker should have died sooner he appears to much
  • gtrko - March 16, 2009 10:21 p.m.

    RIP: Albert Wesker Resident Evil games wouldn't be the same without him *sniffle*
  • Diamondis - March 16, 2009 1:54 p.m.

    As soon as I saw Wesker in the trailers for this game I was upset. Not because I don't like Wesker, because I do... But because I knew he would be the last boss and die =( R.I.P Wekser.
  • Mystery514 - March 14, 2009 5:10 p.m.

    Thanks guys, I really needed this!
  • thekk2007 - March 14, 2009 9:07 a.m.

    I had to do the Final Boss with no ammo on normal!!!!! I used a stun rod keep hitting him untill his heart come out do that for about 8 times and I did it yay
  • NelosAngelos - March 14, 2009 2:38 a.m.

    bout time you beat that bastard down. I only read the boss fights so there wasn't anything to amazing spoiled for me. Can't wait for it.
  • GigaBowser12 - March 13, 2009 9 p.m.

    *Sniffle* RIP Wesker....
  • oryandymackie - March 13, 2009 4:59 p.m.

    If only there were Regenerators in this, that would make this game complete. Disturbing in the jail in RE4 when it lurches slowly towards you down the long corridor.

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