Kingdom Hearts: Birth by Sleep
Aqua and Terra become trapped in the realm of Darkness, and Ven takes a nap in Sora's heart or something. Sora vows to save all of them.
Tom Clancy's HAWX 2
The HAWX squadron defeats the Russians.
Kate is a spy. The Soviets are planning a nuclear strike on Germany to expand their empire.
Professor Layton and the Unwound Future
Above: Also, Luke has to leave Prof.Layton. Fortunately, true friendship is eternal
Future London is really an underground city built by Future Luke who is really a man named Clive, whose parents were killed in the explosion that killed Layton's girlfriend, Claire. He tries to destroy London with a huge machine, but Layton stops him and Clive sees the error of his ways. Celeste is really Claire, pushed into the future momentarily by the explosion, and she disappears after saying a final goodbye to Layton.
Reach falls; you die. Charlie gives it an8.
Phantasy Star Portable 2
You defeat the Sun King and Mika disappears. Emilia is sad, but they're together in their hearts so it's OK.
Dead Rising 2
Phenotrans started the outbreak in order to gather more zombie queens, which they need to manufacture Zombrex. Sullivan is bad. Chuck defeats TK. Katey and Stacey survive.
Front Mission Evolved
The orbital elevator crashes on New York City. Ends with Dylan joining the USN Army as they go to war with the Oceania Cooperative Union.
Ends on a weird cliffhanger where Kate Wilson and Chief Billingham are still trying to escape the ship.