Wii | Submitted by Gene JowersChocolate Bar
If you press the minus symbol between rounds the trainer will eat a candy bar, but it only works once during the match.
Wii | Submitted by thesneak, D ~ HoyHealing
While using the Wiimote and nunchuck control method, when your opponent is down shake the Wiimote and nunchuck repeatedly and part of your health bar will turn white. When your opponent gets up, you will heal all the damage you converted into white. You must be hurt to regain health.
If you're using the classic control style, you can alternate hitting the 1 and 2 button and Mac will get some of his health back.
Punch-Out!! Easter Eggs
Wii | Submitted by NtgraHidden Donkey Kong
Donkey Kong can be seen in the cheering crowd. You can see him after you knock an opponent down. Look towards the upper right section.
Wii | Submitted by Unknown UserChampions Mode
Win 10 bouts in Mac's Last Stand.
Wii | Submitted by Unknown UserUnlock Character Audio
In Exhibition mode complete the 3 challenges on any character and unlock their audio gallery
Wii | Submitted by Unknown UserUnlock Donkey Kong for Exhibition
If you face Donkey Kong in Last Stand mode, you unlock him to fight for Exhibition mode.
Wii | Submitted by McManlyUnlockable Modes
Last Stand Mode - Defeat Mr. Sandman in Title Defense Mode
Major Circuit - Win the Minor Circuit Championship Title
Title Defense Mode - Win the World Circuit Championship Title
World Circuit - Win the Major Circuit Championship Title
Wii | Submitted by UnknownHead Protecting Helmet
In story mode, lose 100 times and you'll unlock the shameful yet helpful helmet, like the one Glass Joe has in the second fight.