Your playing professional style poker players, they do not normally play very many loose hands so you have plenty of room to bluff. Don't be afraid to throw some chips out there and see what happens. A strong raise when you dont have top hand or draw usually indicates a hand. Even if they have nothing (i.e. a pair of 2's J kicker) they usually out draw you (i.e. J on the turn) I have experimented and called hands I knew I was beat on just to prove they raised immensely with nothing but will beat you out.
Once in a while you will have a draw, even if needing runner runner, that will take the hand no doubt. Usually a player will make strong moves on the pot making it hard to call. If you have the chips to gamble with take the risk, one pay off usually makes up for a few mishaps. example of a hand would be AJ hearts, and flop comes Kc 5s 3h ~ someone will bet the K, in this case you have runner runner possibilities for a straight high or low, as well as a runner runner flush possibility, and 1 over with a face kicker. Now even tho the flop shows no signs of you hitting, your outs give you enough odds to call, and can pay off huge because the players betting will self commit, and you can re raise and usually get a call or re raise all in (last effort bluff) or a fold on a re raise all in if you dont hit, but another strong draw comes, it is very likely you can steal the pot.
Submitted by Dustin Hehmann