The biggest difference from Culture Shock is that this time, you'll have a little more freedom to mess around, setting off actions and conversations that serve no purpose other than to be silly. Want to tell your sitcom landlord flat-out that you're trying to hide a cow from him, just to get a rise out of the classically trained chicken who plays him? Go right ahead. Feel like harmlessly shooting up the neighborhood convenience store to hear what the owner will say? Sure. You can even let Max babble about himself for at length on national TV, just to hear the dulcet strains of his squeaky little voice.
While it's more interesting and a little longer than the first episode, don't expect any great challenge from Situation: Comedy's puzzles. They're pretty clever and all, but so long as you explore everywhere, talk to everyone and don't mind a little trial and error, most of them won't give you any trouble. This is meant to be fun and breezy, not to send you hunting for hints.