Resident Evil 5 Strategy guide and Boss guide

Acts 1 and 2 | Acts 3 and 4 | Act 5 | Act 6 

Hot on the heels of Irving our intrepid pair hijack a hovercraft and head towards a suspicious oil refinery. Irving’s trapped, but the story doesn’t end there.

And now for something slightly different. Resident Evil’s first vehicle section.
You need four slate pieces to make it to the native village, which are dotted about the lake’s perimeter.


The Beast Slate is lying by the dead agent at the very start of the Act. Enjoy the peace while it lasts; the majini will act soon enough.

Hop back in the boat and take a left. The Warrior Slate in the hut is straight ahead, which is when the natives will make their move.

When you return to the lake you’ll be trapped until everybody’s dead. Give Sheva a rifle to pick the snipers off, and dodge their projectiles by using the boat’s boost.

The Raptor Slate can be found towards the far right of the lake. When wading through the water just sprint past the crocodiles – don’t fight them!

Finally, the Shaman Slate lives in the top left set of huts. Boost Sheva up the right ladder at the end of the path to find it.

Another siege awaits, only this time there’s nowhere to hide.

The two giant majini are easily as powerful as the Executioner. It wouldn’t be at all silly to use your rocket right now in our opinion.

Enter the hut on the far side of the village and you can kick flaming torches from the top floor. The majini can jump though, so it’s not safe to be up here for long.

Stand on the holes in the ground and these spikes will skewer you. Run past them with majini in pursuit, however, and you’ll kill them instead.

If you need to escape send Sheva to the drawbridge crank and open the door up ahead. The level exit’s only seconds away.


The claustrophobic oil refinery has three valves and two chainsaw majini to contend with. Here's what to do.

First things first: kill everyone. Only then is it safe to turn the valve high up in the middle of the refinery.

Now pull one of the levers to activate the zip line to access the second valve. Once it’s turned a chainsaw majini will suddenly appear, determined to slice you up.

You’ll struggle if you ignore him so find space about the middle platform and shoot with absolutely everything you’ve got.

Just head for the open exit after valve three (ignore Chainsaw No 2), ready to blast the three villagers that appear as you approach.


When Irving escapes by boat a timer will appear – don’t panic!

Preparation helps. When you exit the warehouse equip the shotgun and place grenades on a quick-swap button. It sounds silly, but take your time here – less haste, more speed as they say.

Kill the first two waves of enemies with grenades and the shotgun, otherwise you’ll be trapped by the padlock that’s up ahead. A couple of shots will knock this off the door, after which dogs will burst from the hut opposite.

Kill these and the large majini with your shotgun and shoot the two tripwires on the stairs (one at the top, one at the bottom). Now you can ignore the other majini and run.

To finish the game’s first half you’ll need to survive an explosive boat race.

The opening section’s easy - simply aim for the red tankers (and duck when prompted). You’ll hop off the boat twice to pull levers. Lock to cover the second time as two gunners will attack. Shoot them with the rifle and pull the levers sitting below their turrets to progress.

The act's most powerful weapons:


There’s an RPG in the middle of the lake. The small blip towards the top left of the map is a sunken ship with an RPG crate on top. There’s only one round.

S&W Magnum

After the lake you’ll enter the main native village. Head right and the S&W Magnum’s lying on the ground. Stay on your toes: you’ll be ambushed from above.

Eventually you’ll corner the loud-mouth, but he’ll inject himself with a nasty cocktail and transform into a gigantic water monster:

There are four mounted guns on the ship: two grenade launchers (at the front), and two machine guns (at the rear). Pick the grenade launcher and fire at Irving’s flashing weak point

A couple of hits later and these tentacles will emerge. The pale middles are your targets, so hit each one to break the claws clean off before you find yourself skewered

Keep away from the smooth tentacles that hit the deck, otherwise you’ll be pulled into the air. If Sheva is grabbed just shoot the offending limb to free her

Eventually Irving will appear behind the ship. Tell Sheva to man one machine gun and use the other one to fire at his jellified body. It’s not pleasant

This monster bites, so be ready to hit X (360) or square (PS3) to duck under its jaws. Irving will reappear straight after the bite, so keep shooting until he sleeps with the fishes.

During the warehouse escape you need to hold off the act’s third chainsaw majini. Return to the last corner you ran past and keep him at bay from there.

When you’re on the raft get ready to press either RT and LT or X (360) or square (PS3) and a together: four crocodiles will leap out and kill you instantly if you fail.

A network of caves and ruins is your next port of call. The locals here look primitive, but they’ve harnessed the power of the sun with deadly consequences.


Deep into the ruins you’ll be attacked by a stream of giant balls. Ignore the pots  - you can grab them later - and return to the giant crank in the middle. The pair of you will open the exit door… which will then start to close. Great. Time your run so you dash in between the two right balls. The trap will stop and you can then return for that precious ammo.

The next corridor isn’t safe either. You’ll need to sprint (repeatedly press A or X on PS3) and leap over three gaps. The third leap is then followed by another quick-time event.

Forget the majini, your biggest worries in the underground city are the two deadly sunbeams. On second thoughts, don’t forget the majini entirely now.

Make your way over to the sky emblem in the top left corner. There’s plenty of cover here, so duck into an alcove whenever a beam approaches.

When Sheva’s grabbing the emblem you can kill the left beam’s operator. You’ll also be attacked by two giant majini; we never said it was going to be easy.


Act four concludes with you negotiating a series of floors with easy lightbeam puzzles. Grab the mirrors and bounce the light to the circular stones by the lifts. These puzzles are all really simple.

AI Sheva will climb to safety, but a co-op player might not. Do not move any beams in two-player until you know she’s safe; the light’s deadly. To avoid mistakes, don’t kick down the blocks stopping the beams until every mirror’s in place. The final room has a number of alcoves - enemies are inside them so don’t back into the beam when they attack!

It’s back and it’s easy:

This fight is dead simple. Run straight past the Popokarimu and up the staircase

One quick-time event later and it’s all over. More importantly, your dwindling ammunition supply remains untouched

1. There’s plenty of gold tucked away in the ancient ruins. Be sure to search every coffin; you’re going to need the gold to buy those weapon upgrades.

2. You can double a healing spray’s effect by using it when stood next to Sheva. The spray will top up both characters’ health, not just the one with the vial.

Next page: Act 5


  • TotalKillLOL - June 22, 2009 1:44 a.m.

    Still an awsome game and great graphics and display. although I hate how long the last level takes
  • DantezGirl - June 11, 2009 10:37 a.m.

    Very Cool Game Thaanks For The Help
  • Garry - April 13, 2009 8:33 a.m.

    I have dis game It sucks my head. The town wars i think second wars in starting of game it is sooooooooooo difficult. There r infinite Zombies.
  • Redfield32 - April 12, 2009 9:14 p.m.

    Another RE game after this would kinda be umm weird. I mean you killed the Wesker clone umbrella is f*cked over now what? Be like Final Fantasy and do what happened before RE and play as Umbrella Corp instead of BSAA? Im not saying it would be bad I'm just saying what else is there to add really? Im only at the part with the native guys.
  • GYJX - March 29, 2009 7:04 a.m.

    Ok guys Im new so what up To the point Im not good at english but I going to try.... I know a really easy way to kill Wesker at the volcano, it took me less than 5 minutes on veterans mode which is the third level cause once you beat the game on that level it comes a harder level. Anyway, here I go When you hit the rock so Sheva can jump to get to high groud Wesker follows you, he rise his arm, we all know that, we also know that we have to hit his back so he can show the orange thing on his chest. I hope that you guy can understand me..... When he shows that orange thing on his chest his going to walk towards you, shoot the orange thing till he looks hurt I mean he is not going to move get close to him and the circle button will show up on the screen this is on PS3 Chris will jump to weskers back and he is going to ask Sheva to shoot the orange thing Sheva is going to say that she cant shoot that thing unless she shoots through Chris too so instead of that I dont know what options you have as Sheva but she uses her knif and start to slash wesker if you do that correctly Chris is going to jump to the ground and slash his back too and there his dead Sorry for my english I hope that you guy understand me please if you have any questions or you kill wesker the way I did please I beg Send me a mail to this
  • tylerlldsarg56 - March 27, 2009 12:51 a.m.

    its ok in scarinest i guess ive bout beat it
  • MrDanHalen - March 26, 2009 6:26 p.m.

    OK 2 things to add. 1) you can do more damage to Jill by having Chris/Sheva hold her while the other shoots the device on her chest... takes 4 tries instead of 8 2) Wesker is a clone (the whole wesker family are just clones).... just because he looks dead, does not mean he's gone forever.
  • Nefarious1 - March 24, 2009 1:10 a.m.

    @phoenix_wing: your name alone suggests "the return". I seriously hope that the RE series continues on into the distant future. Just want them to bring actual ZOMBIES back to the series... Maybe a 2 player CO-OP S.T.A.R.S mansion/underground facility revisited.
  • Nefarious1 - March 24, 2009 12:53 a.m.

    young gamers...remember, a very high percentage of RE is preparation, timing and alot of hand cannon recoil. 1st thing I would suggest to all who are having problems with Bosses and such is to MAX out your Magnums. Very few baddies can stand a blast from one of them let alone two (head) shots. Hit those missions hard, sit back, relax and push the limits of the'd be suprised at what u can get away with when u get in close enough to most baddies. Beating the game in -5 hours is very reasonable once you've learned your enemies "comfort zones".
  • Samael - March 22, 2009 5:59 p.m.

    "(ignore Chainsaw No 2)" Ugh, easier said than done. And what about the third chainsaw guy that comes when you're covering Josh? God I hate them!
  • phoenix_wings - March 17, 2009 7:19 a.m.

    I surprisingly didn't have too much difficulty with the bosses. Unfortunately, I didn't know that you could just run around and not blow through all of your ammo on Wesker...I should have read the guide first. Lesson learned. RIP Wesker...I've got to say that the best way to go would have to be in a volcano...I really hope he didn't make a clone of himself or something. Don't get me wrong, I love the RE series, it's just that I think it's time to close the book on this iconic series. And of course the reCaptcha is Continued Dalai
  • HorrorGod - March 17, 2009 6:16 a.m.

    I just beat RE5 today. As a fan of the series (Resident Evil 1 was the reason I bought a Playstation in '96) I have to say I think this was the best one yet. It was nice that it came back to the original characters that started it all. (After Leon got his own game with 4) Anyway, I just wanted to add to the tips and let everyone know you can defeat Wesker in the end with just a QTE. After you beat up the rock and have Sheva join you, you will have the last battle with Wesker in the middle of the circle area. DON'T RUN AWAY. I was screwed on ammo on this point and I could NOT beat him. I would shoot and shoot until his weak spot would show, and I'd shoot more, until my guns went "click". Finally I just ran up to him to see if I could do a QTE (when his weak spot was visible on his chest) and it allowed me to have a QTE. I held him down and Sheva began slashing away with her knife. BOOM, he was down and out. MUCH easier than what other people have been saying on forums (about stocking up on ammo and blasting it.) Hope this helps anyone who may be stuck at this part.
  • darknessexzero - March 17, 2009 3:21 a.m.

    I think wesker should have died sooner he appears to much
  • gtrko - March 16, 2009 10:21 p.m.

    RIP: Albert Wesker Resident Evil games wouldn't be the same without him *sniffle*
  • Diamondis - March 16, 2009 1:54 p.m.

    As soon as I saw Wesker in the trailers for this game I was upset. Not because I don't like Wesker, because I do... But because I knew he would be the last boss and die =( R.I.P Wekser.
  • Mystery514 - March 14, 2009 5:10 p.m.

    Thanks guys, I really needed this!
  • thekk2007 - March 14, 2009 9:07 a.m.

    I had to do the Final Boss with no ammo on normal!!!!! I used a stun rod keep hitting him untill his heart come out do that for about 8 times and I did it yay
  • NelosAngelos - March 14, 2009 2:38 a.m.

    bout time you beat that bastard down. I only read the boss fights so there wasn't anything to amazing spoiled for me. Can't wait for it.
  • GigaBowser12 - March 13, 2009 9 p.m.

    *Sniffle* RIP Wesker....
  • oryandymackie - March 13, 2009 4:59 p.m.

    If only there were Regenerators in this, that would make this game complete. Disturbing in the jail in RE4 when it lurches slowly towards you down the long corridor.

Showing 1-20 of 30 comments

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