GTA: San Andreas - Plane Crash
This one's been around for some time, but it's one of the best "holy what the crap" moments you'll likely ever see come out of San Andreas. While out looking for high-altitude drops to base jump from, this guy accidentally gets clipped by a passing plane - a totally random occurrence that makes an awesome scene hilarious. We could do without all the text thrown up on the screen, but the video speaks for itself.
While it's the only one currently on nick11927's page, it's a doozy and he deserves credit. Visit his little corner of YouTube by clicking here.