-The nuke in World in Conflict is AMAZING
-Just about all large explosions in Supreme Commander are insane (and they fit your "big-ass" description nicely)
-The end boss in Crysis blows up quite nicely, but maybe for spoilers...
-Command & Conquer stuff had nice booms
@game-thugsta: If you're gonna do one from the Jak series, you either need to see Krew's bomb blowing up from Jak II, or the Terraformer going up at the end of Jak 3. Heck, you could probably get away with just tossing in a shot of 3's Supernova gun going off and be good.
But all that and nothing from Ratchet & Clank? That series is almost completely built around blowing up everything you come across. It deserves mention in an article like this.