In Castlevania: Lords of Shadow 2, the familiar health crystals have been replaced with a somewhat gorier method of regeneration. Pain Boxes are now distributed throughout levels, but thrusting your arm into their spiky openings thankfully rewards you with a power boost rather than a severed limb!
There are three different types of Pain Boxes, with each adding a crystal to either your life, void, or chaos powers. Some can be found by playing through the story, while others will need to be gathered by backtracking after you have acquired certain powers.
To help you on your way, this guide will show you where every Pain Box is located, ensuring you build up your powers to the highest level possible.